Side Effects of Antacids and Acid Blockers. To understand the side effects of antacids and acid blocking drugs it is useful to examine why they exist, how they work and what they do.
Gastroesophageal reflux disease (GERD) -. – GERD, in which stomach acid moves into the esophagus, causes discomfort and may lead to precancerous changes in the lining of the esophagus.
), famotidine , cimetidine , or ranitidine to reduce gastric acid. Prokinetic agents to increase the forward movement of the GI tract and increase the pressure of the lower esophageal sphincter.